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Dissecting complex transcriptional responses using pathway-level scores based on prior information

BACKGROUND: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathways to changes in the environment of the cells. The use of prior information, either about the function of the protein enco...

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Detalles Bibliográficos
Autores principales: Bussemaker, Harmen J, Ward, Lucas D, Boorsma, Andre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995543/
https://www.ncbi.nlm.nih.gov/pubmed/17903287
http://dx.doi.org/10.1186/1471-2105-8-S6-S6