A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis

The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection. As the gene is highly conserved in the mycobacteria, we deleted the Rv3574 orthologue in Mycobacterium smegm...

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Detalles Bibliográficos
Autores principales: Kendall, Sharon L, Withers, Mike, Soffair, Catherine N, Moreland, Nicole J, Gurcha, Sudagar, Sidders, Ben, Frita, Rosangela, ten Bokum, Annemieke, Besra, Gurdyal S, Lott, J Shaun, Stoker, Neil G
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995591/
https://www.ncbi.nlm.nih.gov/pubmed/17635188
http://dx.doi.org/10.1111/j.1365-2958.2007.05827.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995591/
https://www.ncbi.nlm.nih.gov/pubmed/17635188
http://dx.doi.org/10.1111/j.1365-2958.2007.05827.x

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