A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis

The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection. As the gene is highly conserved in the mycobacteria, we deleted the Rv3574 orthologue in Mycobacterium smegm...

Descripción completa

Detalles Bibliográficos
Autores principales: Kendall, Sharon L, Withers, Mike, Soffair, Catherine N, Moreland, Nicole J, Gurcha, Sudagar, Sidders, Ben, Frita, Rosangela, ten Bokum, Annemieke, Besra, Gurdyal S, Lott, J Shaun, Stoker, Neil G
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995591/
https://www.ncbi.nlm.nih.gov/pubmed/17635188
http://dx.doi.org/10.1111/j.1365-2958.2007.05827.x

Ejemplares similares

Ejemplares similares