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Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham study

BACKGROUND: Brain magnetic resonance imaging (MRI) and cognitive tests can identify heritable endophenotypes associated with an increased risk of developing stroke, dementia and Alzheimer's disease (AD). We conducted a genome-wide association (GWA) and linkage analysis exploring the genetic bas...

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Detalles Bibliográficos
Autores principales: Seshadri, Sudha, DeStefano, Anita L, Au, Rhoda, Massaro, Joseph M, Beiser, Alexa S, Kelly-Hayes, Margaret, Kase, Carlos S, D'Agostino, Ralph B, DeCarli, Charles, Atwood, Larry D, Wolf, Philip A
Formato: Texto
Lenguaje:English
Publicado: BMC 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995608/
https://www.ncbi.nlm.nih.gov/pubmed/17903297
http://dx.doi.org/10.1186/1471-2350-8-S1-S15