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Nullomers: Really a Matter of Natural Selection?

BACKGROUND: Nullomers are short DNA sequences that are absent from the genomes of humans and other species. Assuming that nullomers are the signatures of natural selection against deleterious sequences in humans, the use of nullomers in drug target identification, pesticide development, environmenta...

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Detalles Bibliográficos
Autores principales: Acquisti, Claudia, Poste, George, Curtiss, David, Kumar, Sudhir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995752/
https://www.ncbi.nlm.nih.gov/pubmed/17925870
http://dx.doi.org/10.1371/journal.pone.0001022