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Nullomers: Really a Matter of Natural Selection?
BACKGROUND: Nullomers are short DNA sequences that are absent from the genomes of humans and other species. Assuming that nullomers are the signatures of natural selection against deleterious sequences in humans, the use of nullomers in drug target identification, pesticide development, environmenta...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995752/ https://www.ncbi.nlm.nih.gov/pubmed/17925870 http://dx.doi.org/10.1371/journal.pone.0001022 |