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Cellular mRNA Activates Transcription Elongation by Displacing 7SK RNA

The positive transcription elongation factor P-TEFb is a pivotal regulator of gene expression in higher cells. Originally identified in Drosophila, attention was drawn to human P-TEFb by the discovery of its role as an essential cofactor for HIV-1 transcription. It is recruited to HIV transcription...

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Detalles Bibliográficos
Autores principales: Young, Tara M., Tsai, Michael, Tian, Bin, Mathews, Michael B., Pe'ery, Tsafi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995758/
https://www.ncbi.nlm.nih.gov/pubmed/17925858
http://dx.doi.org/10.1371/journal.pone.0001010