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Ataxin-1 Fusion Partners Alter PolyQ Lethality and Aggregation
Intranuclear inclusion bodies (IBs) are the histopathologic markers of multiple protein folding diseases. IB formation has been extensively studied using fluorescent fusion products of pathogenic polyglutamine (polyQ) expressing proteins. These studies have been informative in determining the cellul...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995763/ https://www.ncbi.nlm.nih.gov/pubmed/17925862 http://dx.doi.org/10.1371/journal.pone.0001014 |