Cargando…

Ataxin-1 Fusion Partners Alter PolyQ Lethality and Aggregation

Intranuclear inclusion bodies (IBs) are the histopathologic markers of multiple protein folding diseases. IB formation has been extensively studied using fluorescent fusion products of pathogenic polyglutamine (polyQ) expressing proteins. These studies have been informative in determining the cellul...

Descripción completa

Detalles Bibliográficos
Autores principales: Rich, Tina, Varadaraj, Archana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995763/
https://www.ncbi.nlm.nih.gov/pubmed/17925862
http://dx.doi.org/10.1371/journal.pone.0001014