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IP receptor-dependent activation of PPARγ by stable prostacyclin analogues

Stable prostacyclin analogues can signal through cell surface IP receptors or by ligand binding to nuclear peroxisome proliferator-activated receptors (PPARs). So far these agents have been reported to activate PPARα and PPARδ but not PPARγ. Given PPARγ agonists and prostacyclin analogues both inhib...

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Detalles Bibliográficos
Autores principales: Falcetti, Emilia, Flavell, David M., Staels, Bart, Tinker, Andrew, Haworth, Sheila. G., Clapp, Lucie H.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997304/
https://www.ncbi.nlm.nih.gov/pubmed/17624303
http://dx.doi.org/10.1016/j.bbrc.2007.06.135