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A kinetic core model of the glucose-stimulated insulin secretion network of pancreatic β cells

The construction and characterization of a core kinetic model of the glucose-stimulated insulin secretion system (GSIS) in pancreatic β cells is described. The model consists of 44 enzymatic reactions, 59 metabolic state variables, and 272 parameters. It integrates five subsystems: glycolysis, the T...

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Detalles Bibliográficos
Autores principales: Jiang, Nan, Cox, Roger D., Hancock, John M.
Formato: Texto
Lenguaje:English
Publicado: Springer New York 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1998884/
https://www.ncbi.nlm.nih.gov/pubmed/17514510
http://dx.doi.org/10.1007/s00335-007-9011-y