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Sodium Ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake

BACKGROUND: Neuroblastoma (NB) is an extra-cranial solid tumour of childhood. In spite of the good clinical response to first-line therapy, complete eradication of NB cells is rarely achieved. Thus, new therapeutic strategies are needed to eradicate surviving NB cells and prevent relapse. Sodium asc...

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Detalles Bibliográficos
Autores principales: Carosio, Roberta, Zuccari, Guendalina, Orienti, Isabella, Mangraviti, Salvatore, Montaldo, Paolo G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000471/
https://www.ncbi.nlm.nih.gov/pubmed/17760959
http://dx.doi.org/10.1186/1476-4598-6-55