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Effect of renal impairment on the pharmacokinetics of exenatide

What is already known about this subject Nonclinical studies have shown that exenatide is primarily cleared by the renal system. It was not known to what degree the clinical pharmacokinetics and tolerability would be affected by increasing renal impairment (RI). What this study adds: Patients with m...

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Detalles Bibliográficos
Autores principales: Linnebjerg, Helle, Kothare, Prajakti A, Park, Soomin, Mace, Kenneth, Reddy, Shobha, Mitchell, Malcolm, Lins, Robert
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000650/
https://www.ncbi.nlm.nih.gov/pubmed/17425627
http://dx.doi.org/10.1111/j.1365-2125.2007.02890.x