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Exogenous overexpression of nerve growth factor in the urinary bladder produces bladder overactivity and altered micturition circuitry in the lumbosacral spinal cord

BACKGROUND: Exogenous NGF or saline was delivered to the detrusor smooth muscle of female rats for a two-week period using osmotic mini-pumps. We then determined: (1) bladder function using conscious cystometry; (2) organization of micturition reflexes using Fos protein expression in lumbosacral (L5...

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Detalles Bibliográficos
Autores principales: Zvara, Peter, Vizzard, Margaret A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000875/
https://www.ncbi.nlm.nih.gov/pubmed/17725832
http://dx.doi.org/10.1186/1472-6793-7-9