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Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells

BACKGROUND: Many studies have shown that mitochondrial dysfunction, complex I inhibition in particular, is involved in the pathogenesis of Parkinson's disease (PD). Rotenone, a specific inhibitor of mitochondrial complex I, has been shown to produce neurodegeneration in rats as well as in many...

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Detalles Bibliográficos
Autores principales: Jin, Jinghua, Davis, Jeanne, Zhu, David, Kashima, Daniel T, Leroueil, Marc, Pan, Catherine, Montine, Kathleen S, Zhang, Jing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000881/
https://www.ncbi.nlm.nih.gov/pubmed/17705834
http://dx.doi.org/10.1186/1471-2202-8-67