Computational modeling of protein mutant stability: analysis and optimization of statistical potentials and structural features reveal insights into prediction model development

BACKGROUND: Understanding and predicting protein stability upon point mutations has wide-spread importance in molecular biology. Several prediction models have been developed in the past with various algorithms. Statistical potentials are one of the widely used algorithms for the prediction of chang...

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Detalles Bibliográficos
Autores principales: Parthiban, Vijaya, Gromiha, M Michael, Abhinandan, Madenhalli, Schomburg, Dietmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000882/
https://www.ncbi.nlm.nih.gov/pubmed/17705837
http://dx.doi.org/10.1186/1472-6807-7-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000882/
https://www.ncbi.nlm.nih.gov/pubmed/17705837
http://dx.doi.org/10.1186/1472-6807-7-54

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