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Computational modeling of protein mutant stability: analysis and optimization of statistical potentials and structural features reveal insights into prediction model development
BACKGROUND: Understanding and predicting protein stability upon point mutations has wide-spread importance in molecular biology. Several prediction models have been developed in the past with various algorithms. Statistical potentials are one of the widely used algorithms for the prediction of chang...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000882/ https://www.ncbi.nlm.nih.gov/pubmed/17705837 http://dx.doi.org/10.1186/1472-6807-7-54 |