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CD8α is expressed by human monocytes and enhances FcγR-dependent responses

BACKGROUND: CD8α enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8α is also found on dendritic cells and rat macrophages, but whether CD8α enhances responses of a partne...

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Detalles Bibliográficos
Autores principales: Gibbings, Derrick J, Marcet-Palacios, Marcelo, Sekar, Yokananth, Ng, Marcus CY, Befus, A Dean
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000912/
https://www.ncbi.nlm.nih.gov/pubmed/17678538
http://dx.doi.org/10.1186/1471-2172-8-12