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CD8α is expressed by human monocytes and enhances FcγR-dependent responses
BACKGROUND: CD8α enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8α is also found on dendritic cells and rat macrophages, but whether CD8α enhances responses of a partne...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000912/ https://www.ncbi.nlm.nih.gov/pubmed/17678538 http://dx.doi.org/10.1186/1471-2172-8-12 |