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Universally Sloppy Parameter Sensitivities in Systems Biology Models
Quantitative computational models play an increasingly important role in modern biology. Such models typically involve many free parameters, and assigning their values is often a substantial obstacle to model development. Directly measuring in vivo biochemical parameters is difficult, and collective...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000971/ https://www.ncbi.nlm.nih.gov/pubmed/17922568 http://dx.doi.org/10.1371/journal.pcbi.0030189 |