Resistance of human glioma to adriamycin in vitro: the role of membrane transport and its circumvention with verapamil.

We have investigated the mechanism of resistance to adriamycin (ADR) of 3 human glioma cell lines in culture. The cell lines had different inherent sensitivities to ADR. Verapamil increased the ADR sensitivities of the 2 most resistant cell lines (G-UVW and G-CCM) by up to 5-fold. This effect was no...

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Detalles Bibliográficos
Autores principales: Merry, S., Fetherston, C. A., Kaye, S. B., Freshney, R. I., Plumb, J. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1986
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001452/
https://www.ncbi.nlm.nih.gov/pubmed/3947509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001452/
https://www.ncbi.nlm.nih.gov/pubmed/3947509

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