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Binding of urokinase to specific receptor sites on human breast cancer membranes.

The high molecular weight form of the plasminogen activator urokinase (54 kD) binds to specific receptor sites on the cell membrane of breast carcinomas by its inactive "A" chain. The binding is of high affinity (range of dissociation constants: 5.6 X 10(-11) to 4 X 10(-10) mol l-1 and the...

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Detalles Bibliográficos
Autores principales: Needham, G. K., Sherbet, G. V., Farndon, J. R., Harris, A. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001562/
https://www.ncbi.nlm.nih.gov/pubmed/3028459