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Effects of cell density on drug-induced cell kill kinetics in vitro (inoculum effect).

The effects of cell density on drug-induced cell kill kinetics were studied by means of clonogenic assay using 3 human leukaemia-lymphoma cell lines. Mitoxantrone, daunorubicin, doxorubicin, vincristine and bleomycin were progressively less efficacious when cell density increased (positive inoculum...

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Detalles Bibliográficos
Autores principales: Ohnuma, T., Arkin, H., Holland, J. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1986
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001630/
https://www.ncbi.nlm.nih.gov/pubmed/2428392