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Haematological toxicity of carboplatin in rats.

In rats a maximal tolerated dose of carboplatin (60 mg kg-1, i.v.) caused severe anaemia, leucopenia and thrombocytopenia. These indices of haematological toxicity were also observed with a maximal tolerated dose of cis-platin (6.5 mg kg-1, i.v.), but reductions in blood cell counts were less than t...

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Detalles Bibliográficos
Autores principales: Siddik, Z. H., Boxall, F. E., Harrap, K. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001698/
https://www.ncbi.nlm.nih.gov/pubmed/3555590