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Pharmacokinetics of ethylenediaminemalonatoplatinum(II) (JM-40) during phase I trial.

Pharmacokinetics of the cis-platin analog ethylenediaminemalonatoplatinum(II) (JM-410) was studied in 28 cycles of 19 patients during the phase I study of this drug. The drug was administered intravenously by short-term (10-60 min) infusion. Doses ranged from 20 to 1,200mg m-2. JM-40 was determined...

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Detalles Bibliográficos
Autores principales: Elferink, F., van der Vijgh, W. J., ten Bokkel Huinink, W. W., Vermorken, J. B., Klein, I., Winograd, B., Knobf, M. K., Simonetti, G., Gall, H. E., McVie, J. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001825/
https://www.ncbi.nlm.nih.gov/pubmed/3689665