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A system for transformation of rat liver cells in vitro by acute treatment with aflatoxin.

Aflatoxin B1 (AFB1) induced rat liver cancer is a well studied system of hepatocarcinogenesis. AFB1 has also been used to transform cultured rat liver derived cells in vitro. Cells in culture often have a reduced capacity to metabolise the AFB1 to its active metabolite, and often prolonged periods o...

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Detalles Bibliográficos
Autores principales: Sinha, S., Hockin, L. J., Neal, G. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002029/
https://www.ncbi.nlm.nih.gov/pubmed/2887193