Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro.

During recent years N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers have been developed as targetable drug carriers. These soluble synthetic polymers are internalized by cells by pinocytosis and they can be tailor-made to include peptidyl side-chains degradable intracellularly by specific lysoso...

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Detalles Bibliográficos
Autores principales: Duncan, R., Kopecková-Rejmanová, P., Strohalm, J., Hume, I., Cable, H. C., Pohl, J., Lloyd, J. B., Kopecek, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002078/
https://www.ncbi.nlm.nih.gov/pubmed/3468994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002078/
https://www.ncbi.nlm.nih.gov/pubmed/3468994

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