Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid).

LM985 has been shown previously to hydrolyse to flavone acetic acid (LM975) in mouse plasma and to produce significant anti-tumour effects in transplantable mouse colon tumours (MAC). It has undergone Phase I clinical trials and dose limiting toxicity was acute reversible hypotension. Substantially...

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Detalles Bibliográficos
Autores principales: Bibby, M. C., Double, J. A., Phillips, R. M., Loadman, P. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002093/
https://www.ncbi.nlm.nih.gov/pubmed/3814485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002093/
https://www.ncbi.nlm.nih.gov/pubmed/3814485

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