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Alloimmune cells consume interleukin-2 and competitively inhibit the anti-tumour effects of interleukin-2.

Adoptive immunotherapy with lymphokine activated killer (LAK) cells and recombinant interleukin-2 (IL-2) is successful in a variety of tumour models in both the normal and the immunocompromised mouse. We investigated the effects of an immune response to an allogeneic challenge on the metabolism of I...

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Detalles Bibliográficos
Autores principales: Eggermont, A. M., Steller, E. P., Matthews, W., Sugarbaker, P. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002132/
https://www.ncbi.nlm.nih.gov/pubmed/2444243