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Human monoclonal antibodies and monoclonal antibody multispecificity.

The majority of human anti-tumour monoclonal antibodies (Mabs) isolated to date have been disappointing. Firstly, they react or cross react with intracellular cytoskeletal proteins or nuclear antigens and therefore are of limited value as blood borne agents. They are also generally of the IgM isotyp...

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Detalles Bibliográficos
Autores principales: Campbell, A. M., Whitford, P., Leake, R. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002384/
https://www.ncbi.nlm.nih.gov/pubmed/3325093