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Increased Carcinogenic Action of Dimethylnitrosamine after Prior Administaion of Carbon Tetrachloride

Rats were given a single dose of dimethylnitrosamine (DMN, 20 mg/kg body weight) alone or 42 or 60 hours after a non-lethal hepatotoxic dose of carbon tetrachloride (CC1(4)) and killed 12 months later. DMN alone produced no tumours in the kidney and a few in the liver, but when given 42 hours after...

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Detalles Bibliográficos
Autores principales: Pound, A. W., Lawson, T. A., Horn, Lorraine
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1973
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008820/
https://www.ncbi.nlm.nih.gov/pubmed/4352790