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The Mechanisms of Action of the Carcinogenic Nitroso and Related Compounds
It is suggested that the proximate carcinogenic forms of dialkylnitrosamines are their oxidation products, which retain the alkylnitrosamino moiety, but have acquired a carbonyl function as a result of omega or beta oxidation of an alkyl group. Such metabolites resemble the locally acting carcinogen...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1973
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2008919/ https://www.ncbi.nlm.nih.gov/pubmed/4758370 |