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Radiosensitization of C3H Mouse Mammary Tumours by a 2-Nitroimidazole Drug

Local tumour control has been determined at 150 days after single doses of 240 kV x-rays given with or without 1 mg/g body weight of the hypoxic cell radiosensitizer Ro-07-0582. The dose required to control 50% of the tumours (TCD50) was reduced from 4380 to 2410 rad, yielding an enhancement ratio o...

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Detalles Bibliográficos
Autores principales: Sheldon, P. W., Foster, J. L., Fowler, J. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009326/
https://www.ncbi.nlm.nih.gov/pubmed/4451633