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Response of rat lung to inhaled tobacco smoke with or without prior exposure to 3,4-benzpyrene (BP) given by intratracheal instillation.
SPF rats were exposed to the smoke from 10 cigarettes per week from the age of 10 weeks until they died. Survival, body weight, tumour incidence and histopathological appearances of the lungs were compared with those for untreated sham exposed rats. Two further groups were given a single dose of 3,4...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1975
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009453/ https://www.ncbi.nlm.nih.gov/pubmed/1156528 |