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Differences in Metabolism of Vinylidene Chloride Between Mice and Rats

The present finding that mice metabolize a greater proportion of an oral dose (50 mg/kg) of vinylidence chloride. (1,1 - dichloroethylene, DCE) than rats implies (a) that the efficiency of DCE metabolism follows the known activity of cytochrome P-450 in the organs of these animals, and (b) that, in...

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Detalles Bibliográficos
Autores principales: Jones, B. K., Hathway, D. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009538/
https://www.ncbi.nlm.nih.gov/pubmed/638019