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Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II

BACKGROUND: Annexin II heavy chain (also called p36, calpactin I) is lost in prostate cancers and in a majority of prostate intraepithelial neoplasia (PIN). Loss of annexin II heavy chain appears to be specific for prostate cancer since overexpression of annexin II is observed in a majority of human...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Rothermund, Christy A, Ayala-Sanmartin, Jesus, Vishwanatha, Jamboor K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC200965/
https://www.ncbi.nlm.nih.gov/pubmed/12962548
http://dx.doi.org/10.1186/1471-2091-4-10