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Split dose cytotoxic experiments with misonidazole.
The toxicity of misonidazole (1-(2-nitroimidazol-1-yl)-3-methoxy-2-propanol) towards mammalian cells in vitro has been determined as a function of O2 tension. Misonidazole under hypoxic conditions (less than 10 Parts/10(6) O2) shows the greatest toxicity. Split-dose experiments indicate that lethal...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
1978
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009678/ https://www.ncbi.nlm.nih.gov/pubmed/687510 |