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Split dose cytotoxic experiments with misonidazole.

The toxicity of misonidazole (1-(2-nitroimidazol-1-yl)-3-methoxy-2-propanol) towards mammalian cells in vitro has been determined as a function of O2 tension. Misonidazole under hypoxic conditions (less than 10 Parts/10(6) O2) shows the greatest toxicity. Split-dose experiments indicate that lethal...

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Detalles Bibliográficos
Autor principal:	Stratford, I. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1978
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009678/ https://www.ncbi.nlm.nih.gov/pubmed/687510

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