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Tumour-necrosis factor from the rabbit. I. Mode of action, specificity and physicochemical properties.

Sera from rabbits injected with BCG and then with endotoxin contain a factor (tumour-necrosis factor TNF) which, even at high dilutions, is cytotoxic in vitro for mouse L cells and some other cell lines. Using a 51Cr-release assay, cytotoxicity was detected as early as 7-8 h after addition of TNF se...

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Detalles Bibliográficos
Autores principales: Matthews, N., Watkins, J. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009711/
https://www.ncbi.nlm.nih.gov/pubmed/698046