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Tumour-necrosis factor from the rabbit. I. Mode of action, specificity and physicochemical properties.
Sera from rabbits injected with BCG and then with endotoxin contain a factor (tumour-necrosis factor TNF) which, even at high dilutions, is cytotoxic in vitro for mouse L cells and some other cell lines. Using a 51Cr-release assay, cytotoxicity was detected as early as 7-8 h after addition of TNF se...
Autores principales: | Matthews, N., Watkins, J. F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1978
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009711/ https://www.ncbi.nlm.nih.gov/pubmed/698046 |
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