Metal chelates as anti-cancer agents. II cytotoxic action of palladium and platinum complexes of 6-mercaptopurine and thioguanine.

The metal complexes Pd(MP)2.2H2O, Pt(MP)2H2O (MPH=6-mercaptopurine), Pt(AMP2.3H2O and Pd3(AMP)4Cl2(AMPH).4H2O (AMPH=thioguanine) have been isolated. They were screened for anti-tumour activity in the L-1210 lymphoid leukaemia test system in mice. All 4 show marked anti-tumour activity, the complex P...

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Detalles Bibliográficos
Autores principales: Das, M., Livingstone, S. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009717/
https://www.ncbi.nlm.nih.gov/pubmed/698049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009717/
https://www.ncbi.nlm.nih.gov/pubmed/698049

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