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Thyroid tumours in rats and hepatomas in mice after griseofulvin treatment.
Griseofulvin, an antibiotic used to treat dermatophystosis, was tested for carcinogenicity in mice, rats and hamsters. Three groups of mice and rats were given the drug in powdered diet in alternating 5-week periods for life, at dose levels of 3.0%, 1.5% and 0.3% (mice) and 2.0%, 1.0% and 0.2% (rats...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1978
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009728/ https://www.ncbi.nlm.nih.gov/pubmed/698038 |