Inhibition of DNA synthesis by nitroheterocycles. I. Correlation with half-wave reduction potential.

Twenty-one nitroheterocycles, including metronidazole, misonidazole and AF-2, were tested for their ability to inhibit DNA synthesis in mouse L-929 cells growing in culture. All those tested inhibited the rate of incorporation of 3H-thymidine into L cells following drug treatment for 4 h under aerob...

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Detalles Bibliográficos
Autor principal: Olive, P. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009968/
https://www.ncbi.nlm.nih.gov/pubmed/475963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009968/
https://www.ncbi.nlm.nih.gov/pubmed/475963

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