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Radiosensitization of E. coli B/r by the cytotoxic agent procarbazine: a hypoxic cell sensitizer preferentially toxic to aerobic cells and easily oxidized.
Procarbazine has been shown to be a hypoxic cell sensitizer of moderate ability in E. coli B/r, with an achievable enhancement ratio of 1.4 at subtoxic concentrations. The drug appears to act in a manner similar to the expected with the electron-affinic radiosensitizers. However, procarbazine and th...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1979
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009976/ https://www.ncbi.nlm.nih.gov/pubmed/375966 |