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Diet, liver function and dimethylhydrazine-induced gastrointestinal tumours in Wistar rats

Male Wistar rats fed a normal laboratory pelleted diet, when treated s.c. with 1,2-dimethylhydrazine (DMH) 10 mg/kg/wk survived the 24-week experiment, showed no signs of chemical toxicity or macroscopic liver damage, and developed mainly large-bowel tumours. Conversely, male Wistar rats treated wit...

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Detalles Bibliográficos
Autores principales: Castleden, W. M., Shilkin, K. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009977/
https://www.ncbi.nlm.nih.gov/pubmed/444411