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Inactivation by the mitotic inhibitor NY 3170 of human cells in vitro.

Inactivation of NHIK 3025 cells ny the mitotic inhibitor NY 3170 (1-propargyl-5-chloropyrimidin-2-one) was measured as loss of colony-forming ability. NY 3170 at a concentration of 0.15 nM allowed no formation of colonies after 12 days of continuous exposure to the drug. Metaphase arrest after treat...

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Detalles Bibliográficos
Autores principales: Wibe, E., Oftebro, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010025/
https://www.ncbi.nlm.nih.gov/pubmed/475968