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Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma

Numerical and structural centrosome abnormalities are detected in various human malignancies and have been implicated in the formation of multipolar mitoses, chromosome missegregation, and chromosomal instability. Despite this association between centrosome abnormalities and cancerous growth, a caus...

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Detalles Bibliográficos
Autores principales: Duensing, Stefan, Lee, Benjamin H, Cin, Paola Dal, Münger, Karl
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC201009/
https://www.ncbi.nlm.nih.gov/pubmed/14498992
http://dx.doi.org/10.1186/1476-4598-2-30