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Enhanced killing of mammalian cells by radiation combined with m-AMSA.

m-AMSA is an intercalating agent at present on Phase II trial as a chemotherapeutic drug. A 30 min exposure of Chinese hamster (Line V79-753B) cells to submicromolar concentrations of m-AMSA killed 50% of the cells. The survivors had an enhanced sensitivity to radiation-induced cell killing. Dependi...

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Detalles Bibliográficos
Autores principales: Roberts, P. B., Millar, B. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010567/
https://www.ncbi.nlm.nih.gov/pubmed/6893934