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Enhanced killing of mammalian cells by radiation combined with m-AMSA.
m-AMSA is an intercalating agent at present on Phase II trial as a chemotherapeutic drug. A 30 min exposure of Chinese hamster (Line V79-753B) cells to submicromolar concentrations of m-AMSA killed 50% of the cells. The survivors had an enhanced sensitivity to radiation-induced cell killing. Dependi...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1980
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010567/ https://www.ncbi.nlm.nih.gov/pubmed/6893934 |