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In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin.
I have studied the effects on growth of two tumours in mice and on host toxicity, of combining Misonidazole (MISO) or Metronidazole (METRO) with Methotrexate (MTX)-5-fluorouracil (FU) or Adriamycin (ADR). The nitroimidazoles alone had no effect on the growth of either tumour, but MISO (1 mg/g) led t...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1980
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010590/ https://www.ncbi.nlm.nih.gov/pubmed/7459220 |