In vitro metabolism of misonidazole.

Misonidazole (MISO) is a nitroimidazole drug currently undergoing clinical trials as a radiosensitizer of hypoxic tumour cells. The drug is also toxic to such cells, probably because of metabolic activation of the nitro group under hypoxia. The metabolic fate of 14C-labelled MISO is examined, using...

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Detalles Bibliográficos
Autores principales: Josephy, P. D., Palcic, B., Skarsgard, L. D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010618/
https://www.ncbi.nlm.nih.gov/pubmed/7236487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010618/
https://www.ncbi.nlm.nih.gov/pubmed/7236487

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