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Repair of O6-methylguanine in rat liver DNA is enhanced by pretreatment with single or multiple doses of aflatoxin B1.

Pretreatment of rats by the repeated administration of certain alkylating carcinogens has been shown to stimulate the removal of O6-alkylguanine from hepatic DNA. Prolonged feeding with the aromatic amide 2-acetylaminofluorene has a similar effect. In this report, aflatoxin B1, an agent from another...

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Detalles Bibliográficos
Autores principales: Chu, Y. H., Craig, A. W., O'Connor, P. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010712/
https://www.ncbi.nlm.nih.gov/pubmed/6788062