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ICRF 159-induced cell-cycle perturbation in vitro: its relationship to inhibition of colony-forming ability.

The effects of single doses of ICRF 159 (Razoxane) on the cell-cycle kinetics of lines of BKH 21S cells in vitro were studied by means of flow micro-fluorometry (FMF). A characteristic accumulation of cells in the 4n DNA region after 6 h in the presence of ICRF 159 was evident in cells which were se...

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Detalles Bibliográficos
Autores principales: Edgar, D. H., Creighton, A. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010729/
https://www.ncbi.nlm.nih.gov/pubmed/7023524